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Year : 2015  |  Volume : 4  |  Issue : 2  |  Page : 64-72

Hematological profile of patients with Acromegaly in Iraq

1 Iraqi center for cancer and medical genetics / Almustansiriya University
2 National center for diabetes / Almustansiriya University

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Source of Support: None, Conflict of Interest: None

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Background: Acromegaly is a disease characterized by growth hormone and insulin like growth factor hypersecretion due mostly to pituitary somatotropic adenoma. The diagnosis of Acromegaly is usually delayed for years exposing patients to slowly evolving chronic complications. Objectives: To explore the value of performing peripheral blood examination as routine work up in monitoring Iraqi patients with Acromegaly. Patients and Methods: This study was conducted on 38 patients with Acromegaly attending the national center for diabetes research and management. Peripheral blood indices were done by hematological analyzer and blood film stained by Gemisa stain for proper cells morphology done at hematological unit in Iraqi center for cancer and genetics research. Results: The patients examined showed higher values compared with control group in platelets indices (MPV and PDW) that were statistically non-significant. The monocyte count was significantly lower in patients compared by control group (p <0.05).Two patients were found to suffer from thrombocytopenia. One male with mild thrombocytopenia, the second is female with moderate thrombocytopenia. One female with moderate iron deficiency anemia. Conclusion: Peripheral blood exam in patients with Acromegaly is highly indicated, low cost and valuable in follow up patients.

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