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Year : 2018  |  Volume : 7  |  Issue : 2  |  Page : 90-92

Primary splenic follicular lymphoma treated with splenectomy and adjuvant chemotherapy; a case report

1 Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
2 Department of Pathology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India

Correspondence Address:
Dr. Rony Benson
Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram - 695 011, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijh.ijh_10_18

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Primary splenic lymphoma is a rare low-grade non-Hodgkin's lymphoma. This is a case of a 52-year-old woman who had an incidental detection of a lesion in the spleen during evaluation for fever which was found to be a case of primary grade III follicular lymphoma of the spleen. The patient was started on rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy postsplenectomy. Rituximab was not added initially as the patient had a high viral load of hepatitis B virus (HBV). The patient completed six cycles of chemotherapy and rituximab added after four cycles when HBV DNA titer became negative. The outcome in patients with primary follicular lymphoma is good with splenectomy followed by multi-agent chemotherapy.

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