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Outcome of adult acute lymphoblastic leukemia, a single-center experience
Hawar Ghareb Khudhur1, Kawa Muhamadamin Hasan2, Ranan Kardagh Polus3, Ahmed Khudair Yassin2, Nawsherwan Sadiq Mohammad4, Saya Salahaldeen Najmaldeen1
1 Clinical Hematology, Nanakali Hospital, Erbil, Kurdistan Region, Iraq
2 Department of Medicine, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region, Iraq
3 Department of Pathology and Medicine, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region, Iraq
4 Laboratory Hematopathologist, Nanakali Hospital, Erbil, Kurdistan Region, Iraq
Correspondence Address:
Hawar Ghareb Khudhur,
Clinical Hematology, Nanakali Hospital, Erbil, Kurdistan Region
Iraq
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/ijh.ijh_41_22
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BACKGROUND: Adult acute lymphoblastic leukemia (ALL) has a dismal outcome within the optimal situations as the 5-year overall survival (OS) is not reaching 40%.
OBJECTIVE: The objective of this study was to evaluate the outcome of adult ALL in Erbil, Iraq, and to see the factors predicting better survival among them.
PATIENTS AND METHODS: We analyzed data from 71 adult ALL patients aged 14–81 years (mean age: 28.6 years). Diagnosis is based on the peripheral blood film, bone marrow examination, and flow cytometry.
RESULTS: The median OS was 21 months and the median relapse-free survival (RFS) was 13 months. The 3-year OS and the 3-year RFS were 49.3% and 40.8%, respectively, while the 5-year OS and the 5-year RFS were 37.5% and 32.5%, respectively.
CONCLUSION: Factors predicting better survival included in the study; age at diagnosis, remission achievement at first induction, risk assessment, and allogeneic stem cell transplantation optimal response.
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